‘people Assume You’re Crazy For Doing It’: The Melbourne Clinic Infecting Healthy Patients

Australia’s first unit dedicated to human challenge trials for novel vaccines and treatments has opened. But what are the ethics of infecting healthy people – and who would do it?

Green plants, cool tones, casually placed scatter cushions: this living room in East Melbourne could belong to – or at least, be rented by – any millennial. The squeaky corridor floors are a giveaway, though; along with the beds on wheels.

This isn’t a real estate opportunity, but Doherty Clinical Trials (DCT) – Australia’s first unit dedicated to human challenge studies, where trial participants are given a dose of an infectious disease in a controlled setting. An offshoot of the Peter Doherty Institute for Infection and Immunity at the University of Melbourne, it opens on Monday – a breeding ground, its proprietors hope, for discoveries that may redefine the future of disease.

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